SATA Crosslinker Reagent

PRODUCT

SATA Crosslinker Reagent

E020W

SATA is a short-chain (2.8 angstroms spacer arm) reagent for covalent modification of primary amines with a protected sulfhydryl, simulating a crosslinking reagent. SATA reacts with primary amines at pH 7-9 and the resulting modified molecule contains a protected reactive group, which can be deprotected to give the reactive thiol by treatment with hydroxylamine-HCl.

Before deprotection, the modified molecule can be stored indefinitely.
Sulfhydryl groups are important in protein chemistry modification, but are not always present in the molecule of interest.

Properties for SATA Crosslinker Reagent

Features Non cleavable, amine to thiol modification reagent
Name N-Succinimidyl (acetylthio)acetate
Linear formula C8H9NO5S
Molecular weight 231.20 g/mol
Melting point 90-93 °C
Storage Desiccated at -20 °C under Argon. Product is shipped at ambient temperature
Assay ≥ 99%
Identity (NMR) Complies
Solubility DMSO, DMF. Water insoluble

References for SATA Crosslinker Reagent

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