MBS, is a heterobifunctional amine to sulfhydryl crosslinking reagent.MBS contains one NHS ester group and a maleimide reactive group at each end of a small aromatic spacer.The sulfo-NHS ester groups readily react towards primary amines at pH 7-9.The maleimide group reacts towards sulfhydryl (or thiol) groups at pH 6.5-7.5.MBS is not water soluble and must be dissolved in an organic solvent such as DMSO or DMF prior to use.
Properties for MBS
|Features||Water-insoluble and non cleavable|
|Name||3-Maleimidobenzoic acid N-hydroxysuccinimide ester, m-maleimidobenzoyl-N-hydroxysuccinimide ester|
|Molecular weight||314.30 g/mol|
|Melting point||175-177 °C|
|Storage||Desiccated at -20 °C under Argon. Product is shipped at ambient temperature|
|Solubility||DMSO, DMF. Water insoluble|
References for MBS
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