MBS Crosslinker Reagent


MBS Crosslinker Reagent


MBS, is a heterobifunctional amine to sulfhydryl crosslinking reagent. MBS contains one NHS ester group and a maleimide reactive group at each end of a small aromatic spacer. The sulfo-NHS ester groups readily react towards primary amines at pH 7-9.

The maleimide group reacts towards sulfhydryl (or thiol) groups at pH 6.5-7.5.
MBS is not water soluble and must be dissolved in an organic solvent such as DMSO or DMF prior to use.

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Properties for MBS Crosslinker Reagent

Features Water-insoluble and non cleavable
Name 3-Maleimidobenzoic acid N-hydroxysuccinimide ester, m-maleimidobenzoyl-N-hydroxysuccinimide ester
Linear formula C15H10N2O6
Molecular weight 314.30 g/mol
Melting point 175-177 °C
Storage Desiccated at -20 °C under Argon. Product is shipped at ambient temperature
Assay ≥ 97%
Identity (NMR) Complies
Solubility DMSO, DMF. Water insoluble

References for MBS Crosslinker Reagent

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