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Luminescent Reagents for DNA Analysis

I.1.2. P.O.R. F.E.S.R. 2007-2013 – PRRIITT/3.1 (European and Regional Funds)

The objective of the project was the synthesis and characterization of new conjugates fluorophore-dideoxy- and deoxynucleotides nucleotides. The conjugation reaction was based the so-called “click” reaction, which is much more efficient than amide-forming conventional methods.

The results from this project allowed Cyanagen to apply for the patent “Kit and method for the labeling of biomolecules” US2011092676, in addition to an important product line, CHROMIS Azide.

The project was carried out with the Laboratoio per le Tecnologie delle Terapie Avanzate - L.T.T.A. (ex Biopharmanet) - Department Of Experimental Medicine and Diagnostics, Ferrara University and Department of Organic Chemistry “A. MANGINI”­ , University of Bologna.