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The objective of the project was the synthesis and characterization of new conjugates fluorophore-dideoxy- and deoxynucleotides nucleotides. The conjugation reaction was based the so-called “click” reaction, which is much more efficient than amide-forming conventional methods.
The project was carried out with the Laboratoio per le Tecnologie delle Terapie Avanzate - L.T.T.A. (ex Biopharmanet) - Department Of Experimental Medicine and Diagnostics, Ferrara University and Department of Organic Chemistry “A. MANGINI” , University of Bologna.